Testosterone in Women

Hormone therapy for menopause has traditionally focused on estrogen with some progesterone in the conversation. But another hormone is increasingly becoming part of the conversation: testosterone.

In fact, interest has grown enough that the FDA is holding a scientific workshop today dedicated to testosterone use in menopausal women. Researchers and clinicians are examining what we know—and what we still need to learn—about testosterone's effects on sexual function, mood, cognition, muscle and bone health, and long-term safety.

Women naturally produce testosterone, although at substantially lower levels than men. Some women experience symptoms during perimenopause and menopause that prompt a discussion about testosterone therapy. These symptoms include low libido, fatigue, depression, brain fog, and lowered muscle mass.

Testosterone products marketed in the United States are generally formulated and dosed for men. This creates a practical challenge when clinicians determine that testosterone therapy is appropriate for a female patient. Compounding pharmacies can prepare individualized testosterone formulations in strengths and dosage forms prescribed by a healthcare provider when a patient's clinical needs cannot be met by an FDA-approved product. Because women's testosterone doses are typically much lower than doses used in men, accurate formulation, dosing, application instructions, and follow-up are particularly important. Rivertown Compounding uses topi-click dosing containers that measure a 1/4 gram dose per click.